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TREM2 mRNA Expression in Leukocytes Is Increased in Alzheimer’s Disease and Schizophrenia
TREM2 and TYROBP are causal genes for Nasu–Hakola disease (NHD), a rare autosomal recessive disease characterized by bone lesions and early-onset progressive dementia. TREM2 forms a receptor signaling complex with TYROBP, which triggers the activation of immune responses in macrophages and dendritic...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557831/ https://www.ncbi.nlm.nih.gov/pubmed/26332043 http://dx.doi.org/10.1371/journal.pone.0136835 |