TREM2 mRNA Expression in Leukocytes Is Increased in Alzheimer’s Disease and Schizophrenia

TREM2 and TYROBP are causal genes for Nasu–Hakola disease (NHD), a rare autosomal recessive disease characterized by bone lesions and early-onset progressive dementia. TREM2 forms a receptor signaling complex with TYROBP, which triggers the activation of immune responses in macrophages and dendritic...

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Detalles Bibliográficos
Autores principales: Mori, Yoko, Yoshino, Yuta, Ochi, Shinichiro, Yamazaki, Kiyohiro, Kawabe, Kentaro, Abe, Masao, Kitano, Tomoji, Ozaki, Yuki, Yoshida, Taku, Numata, Shusuke, Mori, Takaaki, Iga, Junichi, Kuroda, Norio, Ohmori, Tetsuro, Ueno, Shu-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557831/
https://www.ncbi.nlm.nih.gov/pubmed/26332043
http://dx.doi.org/10.1371/journal.pone.0136835

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