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Sequence variation in telomerase reverse transcriptase (TERT) as a determinant of risk of cardiovascular disease: the Atherosclerosis Risk in Communities (ARIC) study

BACKGROUND: Telomerase reverse transcriptase (TERT) maintains telomere ends during DNA replication by catalyzing the addition of short telomere repeats. The expression of telomerase is normally repressed in somatic cells leading to a gradual shortening of telomeres and cellular senescence with aging...

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Detalles Bibliográficos
Autores principales: Bressler, Jan, Franceschini, Nora, Demerath, Ellen W., Mosley, Thomas H., Folsom, Aaron R., Boerwinkle, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557920/
https://www.ncbi.nlm.nih.gov/pubmed/26201603
http://dx.doi.org/10.1186/s12881-015-0194-x