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Sequence variation in telomerase reverse transcriptase (TERT) as a determinant of risk of cardiovascular disease: the Atherosclerosis Risk in Communities (ARIC) study
BACKGROUND: Telomerase reverse transcriptase (TERT) maintains telomere ends during DNA replication by catalyzing the addition of short telomere repeats. The expression of telomerase is normally repressed in somatic cells leading to a gradual shortening of telomeres and cellular senescence with aging...
Autores principales: | Bressler, Jan, Franceschini, Nora, Demerath, Ellen W., Mosley, Thomas H., Folsom, Aaron R., Boerwinkle, Eric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557920/ https://www.ncbi.nlm.nih.gov/pubmed/26201603 http://dx.doi.org/10.1186/s12881-015-0194-x |
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