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Circulating CXCR5(+)CD4(+) T Follicular-Like Helper Cell and Memory B Cell Responses to Human Papillomavirus Vaccines

Through the interaction of T follicular helper (Tfh) cells and B cells, efficacious vaccines can generate high-affinity, pathogen-neutralizing antibodies, and memory B cells. Using CXCR5, CXCR3, CCR6, CCR7, PD1, and ICOS as markers, Tfh-like cells can be identified in the circulation and be classifi...

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Detalles Bibliográficos
Autores principales: Matsui, Ken, Adelsberger, Joseph W., Kemp, Troy J., Baseler, Michael W., Ledgerwood, Julie E., Pinto, Ligia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557948/
https://www.ncbi.nlm.nih.gov/pubmed/26333070
http://dx.doi.org/10.1371/journal.pone.0137195