Antioxidant Treatment and Induction of Autophagy Cooperate to Reduce Desmin Aggregation in a Cellular Model of Desminopathy

Desminopathies, a subgroup of myofibrillar myopathies (MFMs), the progressive muscular diseases characterized by the accumulation of granulofilamentous desmin-positive aggregates, result from mutations in the desmin gene (DES), encoding a muscle-specific intermediate filament. Desminopathies often l...

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Detalles Bibliográficos
Autores principales: Cabet, Eva, Batonnet-Pichon, Sabrina, Delort, Florence, Gausserès, Blandine, Vicart, Patrick, Lilienbaum, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557996/
https://www.ncbi.nlm.nih.gov/pubmed/26333167
http://dx.doi.org/10.1371/journal.pone.0137009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557996/
https://www.ncbi.nlm.nih.gov/pubmed/26333167
http://dx.doi.org/10.1371/journal.pone.0137009

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