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Human bone marrow niche chemoprotection mediated by cytochrome p450 enzymes

Substantial evidence now demonstrates that interactions between the tumor microenvironment and malignant cells are a critical component of clinical drug resistance. However, the mechanisms responsible for microenvironment-mediated chemoprotection remain unclear. We showed that bone marrow (BM) strom...

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Detalles Bibliográficos
Autores principales: Alonso, Salvador, Su, Meng, Jones, Jace W., Ganguly, Sudipto, Kane, Maureen A., Jones, Richard J., Ghiaur, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558124/
https://www.ncbi.nlm.nih.gov/pubmed/25915157