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Loss of CX3CR1 increases accumulation of inflammatory monocytes and promotes gliomagenesis

The most abundant populations of non-neoplastic cells in the glioblastoma (GBM) microenvironment are resident microglia, macrophages and infiltrating monocytes from the blood circulation. The mechanisms by which monocytes infiltrate into GBM, their fate following infiltration, and their role in GBM...

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Detalles Bibliográficos
Autores principales: Feng, Xi, Szulzewsky, Frank, Yerevanian, Alexan, Chen, Zhihong, Heinzmann, David, Rasmussen, Rikke Darling, Alvarez-Garcia, Virginia, Kim, Yeonghwan, Wang, Bingcheng, Tamagno, Ilaria, Zhou, Hao, Li, Xiaoxia, Kettenmann, Helmut, Ransohoff, Richard M., Hambardzumyan, Dolores
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558137/
https://www.ncbi.nlm.nih.gov/pubmed/25987130