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Loss of CX3CR1 increases accumulation of inflammatory monocytes and promotes gliomagenesis
The most abundant populations of non-neoplastic cells in the glioblastoma (GBM) microenvironment are resident microglia, macrophages and infiltrating monocytes from the blood circulation. The mechanisms by which monocytes infiltrate into GBM, their fate following infiltration, and their role in GBM...
Autores principales: | Feng, Xi, Szulzewsky, Frank, Yerevanian, Alexan, Chen, Zhihong, Heinzmann, David, Rasmussen, Rikke Darling, Alvarez-Garcia, Virginia, Kim, Yeonghwan, Wang, Bingcheng, Tamagno, Ilaria, Zhou, Hao, Li, Xiaoxia, Kettenmann, Helmut, Ransohoff, Richard M., Hambardzumyan, Dolores |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558137/ https://www.ncbi.nlm.nih.gov/pubmed/25987130 |
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