Inhibition of thioredoxin 1 leads to apoptosis in drug-resistant multiple myeloma

Multiple myeloma (MM) is a hematological malignancy characterized by the aberrant accumulation of clonal plasma cells in the bone marrow. Despite recent advancement in anti-myeloma treatment, MM remains an incurable disease. This study showed higher intrinsic oxidative stress and higher Trx1 and Trx...

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Detalles Bibliográficos
Autores principales: Raninga, Prahlad V., Di Trapani, Giovanna, Vuckovic, Slavica, Bhatia, Maneet, Tonissen, Kathryn F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558160/
https://www.ncbi.nlm.nih.gov/pubmed/25945832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558160/
https://www.ncbi.nlm.nih.gov/pubmed/25945832

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