DNA strand breaks induced by nuclear hijacking of neuronal NOS as an anti-cancer effect of 2-methoxyestradiol

2-Methoxyestradiol (2-ME) is a physiological metabolite of 17β-estradiol. At pharmacological concentrations, 2-ME inhibits colon, breast and lung cancer in tumor models. Here we investigated the effect of physiologically relevant concentrations of 2-ME in osteosarcoma cell model. We demonstrated tha...

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Detalles Bibliográficos
Autores principales: Gorska, Magdalena, Kuban-Jankowska, Alicja, Zmijewski, Michal, Gammazza, Antonella Marino, Cappello, Francesco, Wnuk, Maciej, Gorzynik, Monika, Rzeszutek, Iwona, Daca, Agnieszka, Lewinska, Anna, Wozniak, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558163/
https://www.ncbi.nlm.nih.gov/pubmed/25972363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558163/
https://www.ncbi.nlm.nih.gov/pubmed/25972363

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