Wnt7a is a novel inducer of β-catenin-independent tumor-suppressive cellular senescence in lung cancer

Cellular senescence is an initial barrier for carcinogenesis. However, the signaling mechanisms that trigger cellular senescence are incompletely understood, particularly in vivo. Here we identify Wnt7a as a novel upstream inducer of cellular senescence. In two different mouse strains (C57Bl/6J and...

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Detalles Bibliográficos
Autores principales: Bikkavilli, R K, Avasarala, S, Van Scoyk, M, Arcaroli, J, Brzezinski, C, Zhang, W, Edwards, M G, Rathinam, M K K, Zhou, T, Tauler, J, Borowicz, S, Lussier, Y A, Parr, B A, Cool, C D, Winn, R A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558401/
https://www.ncbi.nlm.nih.gov/pubmed/25728679
http://dx.doi.org/10.1038/onc.2015.2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558401/
https://www.ncbi.nlm.nih.gov/pubmed/25728679
http://dx.doi.org/10.1038/onc.2015.2

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