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Applying NGS Data to Find Evolutionary Network Biomarkers from the Early and Late Stages of Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is a major liver tumor (~80%), besides hepatoblastomas, angiosarcomas, and cholangiocarcinomas. In this study, we used a systems biology approach to construct protein-protein interaction networks (PPINs) for early-stage and late-stage liver cancer. By comparing the net...

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Detalles Bibliográficos
Autores principales: Wong, Yung-Hao, Wu, Chia-Chou, Lin, Chih-Lung, Chen, Ting-Shou, Chang, Tzu-Hao, Chen, Bor-Sen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558430/
https://www.ncbi.nlm.nih.gov/pubmed/26366411
http://dx.doi.org/10.1155/2015/391475