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Expression profiling pre-diabetic mice to uncover drugs with clinical application to type 1 diabetes

In the NOD mouse model of type 1 diabetes (T1D), genetically identical mice in the same environment develop diabetes at different rates. Similar heterogeneity in the rate of progression to T1D exists in humans, but the underlying mechanisms are unclear. Here, we aimed to discover peripheral blood (P...

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Detalles Bibliográficos
Autores principales: Pang, Dimeng, Irvine, Katharine M, Mehdi, Ahmed M, Thomas, Helen E, Harris, Mark, Hamilton-Williams, Emma E, Thomas, Ranjeny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558439/
https://www.ncbi.nlm.nih.gov/pubmed/26366287
http://dx.doi.org/10.1038/cti.2015.17