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Expression profiling pre-diabetic mice to uncover drugs with clinical application to type 1 diabetes
In the NOD mouse model of type 1 diabetes (T1D), genetically identical mice in the same environment develop diabetes at different rates. Similar heterogeneity in the rate of progression to T1D exists in humans, but the underlying mechanisms are unclear. Here, we aimed to discover peripheral blood (P...
Autores principales: | Pang, Dimeng, Irvine, Katharine M, Mehdi, Ahmed M, Thomas, Helen E, Harris, Mark, Hamilton-Williams, Emma E, Thomas, Ranjeny |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558439/ https://www.ncbi.nlm.nih.gov/pubmed/26366287 http://dx.doi.org/10.1038/cti.2015.17 |
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