MicroRNA-587 antagonizes 5-FU-induced apoptosis and confers drug resistance by regulating PPP2R1B expression in colorectal cancer

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Drug resistance is one of the major hurdles for cancer treatment. However, the underlying mechanisms are still largely unknown and therapeutic options remain limited. In this study, we show that microRNA (miR)-587 confers resistance to 5-fluorouracil (5-FU)-induced apoptosis in vitro and reduces the...

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Detalles Bibliográficos
Autores principales: Zhang, Y, Talmon, G, Wang, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558495/
https://www.ncbi.nlm.nih.gov/pubmed/26247730
http://dx.doi.org/10.1038/cddis.2015.200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558495/
https://www.ncbi.nlm.nih.gov/pubmed/26247730
http://dx.doi.org/10.1038/cddis.2015.200

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