Silencing NFBD1/MDC1 enhances the radiosensitivity of human nasopharyngeal cancer CNE1 cells and results in tumor growth inhibition

NFBD1 functions in cell cycle checkpoint activation and DNA repair following ionizing radiation (IR). In this study, we defined the NFBD1 as a tractable molecular target to radiosensitize nasopharyngeal carcinoma (NPC) cells. Silencing NFBD1 using lentivirus-mediated shRNA-sensitized NPC cells to ra...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Z, Zeng, Q, Chen, T, Liao, K, Bu, Y, Hong, S, Hu, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558506/
https://www.ncbi.nlm.nih.gov/pubmed/26247734
http://dx.doi.org/10.1038/cddis.2015.214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558506/
https://www.ncbi.nlm.nih.gov/pubmed/26247734
http://dx.doi.org/10.1038/cddis.2015.214

Ejemplares similares