Cargando…

Antigen presentation kinetics control T cell/dendritic cell interactions and follicular helper T cell generation in vivo

The production of high affinity, class switched antibodies produced by B cells hinges on the effective differentiation of T follicular helper (Tfh) cells. Here we define conditions specifically enhancing Tfh differentiation and providing protection in a model of influenza infection. Tfh responses we...

Descripción completa

Detalles Bibliográficos
Autores principales: Benson, Robert A, MacLeod, Megan KL, Hale, Benjamin G, Patakas, Agapitos, Garside, Paul, Brewer, James M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558563/
https://www.ncbi.nlm.nih.gov/pubmed/26258879
http://dx.doi.org/10.7554/eLife.06994