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Antigen presentation kinetics control T cell/dendritic cell interactions and follicular helper T cell generation in vivo
The production of high affinity, class switched antibodies produced by B cells hinges on the effective differentiation of T follicular helper (Tfh) cells. Here we define conditions specifically enhancing Tfh differentiation and providing protection in a model of influenza infection. Tfh responses we...
Autores principales: | Benson, Robert A, MacLeod, Megan KL, Hale, Benjamin G, Patakas, Agapitos, Garside, Paul, Brewer, James M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558563/ https://www.ncbi.nlm.nih.gov/pubmed/26258879 http://dx.doi.org/10.7554/eLife.06994 |
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