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CD154-CD40 T-cell co-stimulation pathway is a key mechanism in kidney ischemia-reperfusion injury
Ischemia-reperfusion occurs in a great many clinical settings and contributes to organ failure or dysfunction. CD154-CD40 signaling in leukocyte–endothelial cell interactions or T-cell activation facilitates tissue inflammation and injury. Here we tested a siRNA anti-CD40 in rodent warm and cold isc...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558568/ https://www.ncbi.nlm.nih.gov/pubmed/25993320 http://dx.doi.org/10.1038/ki.2015.146 |