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Direct synthesis of imino-C-nucleoside analogues and other biologically active iminosugars
Iminosugars have attracted increasing attention as chemical probes, chaperones and leads for drug discovery. Despite several clinical successes, their de novo synthesis remains a significant challenge that also limits their integration with modern high-throughput screening technologies. Herein, we d...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Pub. Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558570/ https://www.ncbi.nlm.nih.gov/pubmed/25903019 http://dx.doi.org/10.1038/ncomms7903 |