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Quantitative fragment analysis of FLT3-ITD efficiently identifying poor prognostic group with high mutant allele burden or long ITD length

Mutation of the fms-like tyrosine kinase 3-internal tandem duplication (FLT3-ITD), which is one of the most frequent genetic alterations, strongly contributes to an increased risk of treatment failure and to poor prognosis. In this study, we established quantitative fragment analysis of FLT3-ITD sim...

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Detalles Bibliográficos
Autores principales: Kim, Y, Lee, G D, Park, J, Yoon, J-H, Kim, H-J, Min, W-S, Kim, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558586/
https://www.ncbi.nlm.nih.gov/pubmed/26832846
http://dx.doi.org/10.1038/bcj.2015.61