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Quantitative fragment analysis of FLT3-ITD efficiently identifying poor prognostic group with high mutant allele burden or long ITD length
Mutation of the fms-like tyrosine kinase 3-internal tandem duplication (FLT3-ITD), which is one of the most frequent genetic alterations, strongly contributes to an increased risk of treatment failure and to poor prognosis. In this study, we established quantitative fragment analysis of FLT3-ITD sim...
Autores principales: | Kim, Y, Lee, G D, Park, J, Yoon, J-H, Kim, H-J, Min, W-S, Kim, M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558586/ https://www.ncbi.nlm.nih.gov/pubmed/26832846 http://dx.doi.org/10.1038/bcj.2015.61 |
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