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Identification of genes associated with methotrexate resistance in methotrexate-resistant osteosarcoma cell lines
BACKGROUND: This study aimed to better understand the mechanisms underlying methotrexate (MTX)—resistance in osteosarcoma. METHODS: The raw transcription microarray data GSE16089 collected from three MTX-sensitive osteosarcoma (Saos-2) cell samples and three MTX-resistant osteosarcoma (Saos-2) cell...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558632/ https://www.ncbi.nlm.nih.gov/pubmed/26337976 http://dx.doi.org/10.1186/s13018-015-0275-8 |