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Identification of genes associated with methotrexate resistance in methotrexate-resistant osteosarcoma cell lines

BACKGROUND: This study aimed to better understand the mechanisms underlying methotrexate (MTX)—resistance in osteosarcoma. METHODS: The raw transcription microarray data GSE16089 collected from three MTX-sensitive osteosarcoma (Saos-2) cell samples and three MTX-resistant osteosarcoma (Saos-2) cell...

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Detalles Bibliográficos
Autores principales: Yang, Xiao-rong, Xiong, Yan, Duan, Hong, Gong, Ren-rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558632/
https://www.ncbi.nlm.nih.gov/pubmed/26337976
http://dx.doi.org/10.1186/s13018-015-0275-8