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Eviction of linker histone H1 by NAP-family histone chaperones enhances activated transcription

BACKGROUND: In the Metazoan nucleus, core histones assemble the genomic DNA to form nucleosome arrays, which are further compacted into dense chromatin structures by the linker histone H1. The extraordinary density of chromatin creates an obstacle for accessing the genetic information. Regulation of...

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Detalles Bibliográficos
Autores principales: Zhang, Qian, Giebler, Holli A., Isaacson, Marisa K., Nyborg, Jennifer K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558729/
https://www.ncbi.nlm.nih.gov/pubmed/26339295
http://dx.doi.org/10.1186/s13072-015-0022-8