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A hypoxic ticket to the bone metastatic niche
Hypoxia is a well-characterized driver of aggressive cancer phenotypes, including metastasis. Accumulating evidence suggests that, in addition to having local effects, the consequences of tumour hypoxia can be systemic, leading to the formation of pre-metastatic niches that can later foster metastat...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558777/ https://www.ncbi.nlm.nih.gov/pubmed/26337273 http://dx.doi.org/10.1186/s13058-015-0635-7 |