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What Fraction of Duplicates Observed in Recently Sequenced Genomes Is Segregating and Destined to Fail to Fix?

Most sequenced eukaryotic genomes show a large excess of recent duplicates. As duplicates age, both the population genetic process of failed fixation and the mutation-driven process of nonfunctionalization act to reduce the observed number of duplicates. Understanding the processes generating the ag...

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Detalles Bibliográficos
Autores principales: Teufel, Ashley I., Masel, Joanna, Liberles, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558857/
https://www.ncbi.nlm.nih.gov/pubmed/26220936
http://dx.doi.org/10.1093/gbe/evv139