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EMSAR: estimation of transcript abundance from RNA-seq data by mappability-based segmentation and reclustering

BACKGROUND: RNA-seq has been widely used for genome-wide expression profiling. RNA-seq data typically consists of tens of millions of short sequenced reads from different transcripts. However, due to sequence similarity among genes and among isoforms, the source of a given read is often ambiguous. E...

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Detalles Bibliográficos
Autores principales: Lee, Soohyun, Seo, Chae Hwa, Alver, Burak Han, Lee, Sanghyuk, Park, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559005/
https://www.ncbi.nlm.nih.gov/pubmed/26335049
http://dx.doi.org/10.1186/s12859-015-0704-z