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Erythropoietin produced by genetic-modified NIH/3T3 fibroblasts enhances the survival of degenerating neurons

BACKGROUND: Erythropoietin (EPO) has potent neuroprotective effects. The short-term delivery of high-dose EPO seemed to improve patients’ neuromuscular functions; however, excessive EPO resulted in systematically high hematocrit and thrombotic risk. In our study, we established a cellular material f...

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Detalles Bibliográficos
Autores principales: Li, Yi-Chin, Chen, Shiu-Jau, Chien, Chung-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559019/
https://www.ncbi.nlm.nih.gov/pubmed/26357589
http://dx.doi.org/10.1002/brb3.356