Trans-species polymorphism in humans and the great apes is generally maintained by balancing selection that modulates the host immune response

Known examples of ancient identical-by-descent genetic variants being shared between evolutionarily related species, known as trans-species polymorphisms (TSPs), result from counterbalancing selective forces acting on target genes to confer resistance against infectious agents. To date, putative TSP...

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Detalles Bibliográficos
Autores principales: Azevedo, Luisa, Serrano, Catarina, Amorim, Antonio, Cooper, David N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559023/
https://www.ncbi.nlm.nih.gov/pubmed/26337052
http://dx.doi.org/10.1186/s40246-015-0043-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559023/
https://www.ncbi.nlm.nih.gov/pubmed/26337052
http://dx.doi.org/10.1186/s40246-015-0043-1

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