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Trans-species polymorphism in humans and the great apes is generally maintained by balancing selection that modulates the host immune response
Known examples of ancient identical-by-descent genetic variants being shared between evolutionarily related species, known as trans-species polymorphisms (TSPs), result from counterbalancing selective forces acting on target genes to confer resistance against infectious agents. To date, putative TSP...
Autores principales: | Azevedo, Luisa, Serrano, Catarina, Amorim, Antonio, Cooper, David N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559023/ https://www.ncbi.nlm.nih.gov/pubmed/26337052 http://dx.doi.org/10.1186/s40246-015-0043-1 |
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