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Pharmacokinetics and safety of ixazomib plus lenalidomide–dexamethasone in Asian patients with relapsed/refractory myeloma: a phase 1 study

BACKGROUND: The oral proteasome inhibitor ixazomib is under phase 3 clinical investigation in multiple myeloma (MM) in combination with lenalidomide–dexamethasone. This study was conducted to investigate the pharmacokinetic and safety profiles of ixazomib, administered with lenalidomide–dexamethason...

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Detalles Bibliográficos
Autores principales: Gupta, Neeraj, Goh, Yeow Tee, Min, Chang-Ki, Lee, Jae Hoon, Kim, Kihyun, Wong, Raymond S. M., Chim, Chor Sang, Hanley, Michael J., Yang, Huyuan, Venkatakrishnan, Karthik, Hui, Ai-Min, Esseltine, Dixie-Lee, Chng, Wee Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559079/
https://www.ncbi.nlm.nih.gov/pubmed/26337806
http://dx.doi.org/10.1186/s13045-015-0198-1