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Nonlinear mixed-effects modelling for single cell estimation: when, why, and how to use it
BACKGROUND: Studies of cell-to-cell variation have in recent years grown in interest, due to improved bioanalytical techniques which facilitates determination of small changes with high uncertainty. Like much high-quality data, single-cell data is best analysed using a systems biology approach. The...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559169/ https://www.ncbi.nlm.nih.gov/pubmed/26335227 http://dx.doi.org/10.1186/s12918-015-0203-x |