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Nonlinear mixed-effects modelling for single cell estimation: when, why, and how to use it

BACKGROUND: Studies of cell-to-cell variation have in recent years grown in interest, due to improved bioanalytical techniques which facilitates determination of small changes with high uncertainty. Like much high-quality data, single-cell data is best analysed using a systems biology approach. The...

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Detalles Bibliográficos
Autores principales: Karlsson, Markus, Janzén, David L.I., Durrieu, Lucia, Colman-Lerner, Alejandro, Kjellsson, Maria C., Cedersund, Gunnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559169/
https://www.ncbi.nlm.nih.gov/pubmed/26335227
http://dx.doi.org/10.1186/s12918-015-0203-x