A novel POLE mutation associated with cancers of colon, pancreas, ovaries and small intestine

In some families there is an increased risk for colorectal cancer, caused by heritable, but often unidentified genetic mutations predisposing to the disease. We have identified the likely genetic cause for disease predisposition in a large family with high burden of colorectal adenomas and carcinoma...

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Detalles Bibliográficos
Autores principales: Hansen, Maren F., Johansen, Jostein, Bjørnevoll, Inga, Sylvander, Anna E., Steinsbekk, Kristin S., Sætrom, Pål, Sandvik, Arne K., Drabløs, Finn, Sjursen, Wenche
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559173/
https://www.ncbi.nlm.nih.gov/pubmed/25860647
http://dx.doi.org/10.1007/s10689-015-9803-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559173/
https://www.ncbi.nlm.nih.gov/pubmed/25860647
http://dx.doi.org/10.1007/s10689-015-9803-2

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