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A novel POLE mutation associated with cancers of colon, pancreas, ovaries and small intestine
In some families there is an increased risk for colorectal cancer, caused by heritable, but often unidentified genetic mutations predisposing to the disease. We have identified the likely genetic cause for disease predisposition in a large family with high burden of colorectal adenomas and carcinoma...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Netherlands
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559173/ https://www.ncbi.nlm.nih.gov/pubmed/25860647 http://dx.doi.org/10.1007/s10689-015-9803-2 |