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Malat1 as an evolutionarily conserved lncRNA, plays a positive role in regulating proliferation and maintaining undifferentiated status of early-stage hematopoietic cells

BACKGROUND: The metastasis-associated lung adenocarcinoma transcription 1 (Malat1) is a highly conserved long non-coding RNA (lncRNA) gene. Previous studies showed that Malat1 is abundantly expressed in many tissues and involves in promoting tumor growth and metastasis by modulating gene expression...

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Detalles Bibliográficos
Autores principales: Ma, Xian-Yong, Wang, Jian-Hui, Wang, Jing-Lan, Ma, Charles X, Wang, Xiao-Chun, Liu, Feng-Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559210/
https://www.ncbi.nlm.nih.gov/pubmed/26335021
http://dx.doi.org/10.1186/s12864-015-1881-x