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Micheliolide overcomes KLF4-mediated cisplatin resistance in breast cancer cells by downregulating glutathione

Micheliolide (MCL) is a promising novel compound with broad-spectrum anticancer activity. However, little is known regarding its action and mechanism in breast cancer. To explore the potential therapeutic application of MCL as a chemosensitivity modulator, this study investigated the effects of MCL...

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Detalles Bibliográficos
Autores principales: Jia, Yongsheng, Zhang, Chunze, Zhou, Liyan, Xu, Huijun, Shi, Yehui, Tong, Zhongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559251/
https://www.ncbi.nlm.nih.gov/pubmed/26356142
http://dx.doi.org/10.2147/OTT.S88661