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Role of high-mobility group box 1 in methamphetamine-induced activation and migration of astrocytes

BACKGROUND: Mounting evidence has indicated that high-mobility group box 1 (HMGB1) is involved in cell activation and migration. Our previous study demonstrated that methamphetamine mediates activation of astrocytes via sigma-1 receptor (σ-1R). However, the elements downstream of σ-1R in this proces...

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Detalles Bibliográficos
Autores principales: Zhang, Yuan, Zhu, Tiebing, Zhang, Xiaotian, Chao, Jie, Hu, Gang, Yao, Honghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559295/
https://www.ncbi.nlm.nih.gov/pubmed/26337661
http://dx.doi.org/10.1186/s12974-015-0374-9