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Marked differences in frequencies of statin therapy relevant SLCO1B1 variants and haplotypes between Roma and Hungarian populations

BACKGROUND: SLCO1B1 polymorphisms are relevant in statin pharmacokinetics. Aim of this study was to investigate the genetic variability and haplotype profile of SLCO1B1 polymorphisms in Roma and Hungarian populations. Genotypes of 470 Roma and 442 Hungarian subjects for c.388A > G, c.521T > C...

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Detalles Bibliográficos
Autores principales: Nagy, Agnes, Sipeky, Csilla, Szalai, Renata, Melegh, Bela Imre, Matyas, Petra, Ganczer, Alma, Toth, Kalman, Melegh, Bela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559300/
https://www.ncbi.nlm.nih.gov/pubmed/26334733
http://dx.doi.org/10.1186/s12863-015-0262-4