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High cortisol in 5-year-old children causes loss of DNA methylation in SINE retrotransposons: a possible role for ZNF263 in stress-related diseases

BACKGROUND: Childhood stress leads to increased risk of many adult diseases, such as major depression and cardiovascular disease. Studies show that adults with experienced childhood stress have specific epigenetic changes, but to understand the pathways that lead to disease, we also need to study th...

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Detalles Bibliográficos
Autores principales: Nätt, Daniel, Johansson, Ingela, Faresjö, Tomas, Ludvigsson, Johnny, Thorsell, Annika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559301/
https://www.ncbi.nlm.nih.gov/pubmed/26339299
http://dx.doi.org/10.1186/s13148-015-0123-z