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Tissue biodistribution of intravenously administrated titanium dioxide nanoparticles revealed blood-brain barrier clearance and brain inflammation in rat
BACKGROUND: Notwithstanding increasing knowledge of titanium dioxide nanoparticles (TiO(2) NPs) passing through biological barriers, their biodistribution to the central nervous system (CNS) and potential effects on blood-brain barrier (BBB) physiology remain poorly characterized. METHODS: Here, we...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559366/ https://www.ncbi.nlm.nih.gov/pubmed/26337446 http://dx.doi.org/10.1186/s12989-015-0102-8 |