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Dual Opposing Roles of Metallothionein Overexpression in C57BL/6J Mouse Pancreatic β-Cells

BACKGROUND: Growing evidence indicates that oxidative stress (OS), a persistent state of excess amounts of reactive oxygen species (ROS) along with reactive nitrogen species (RNS), plays an important role in insulin resistance, diabetic complications, and dysfunction of pancreatic β-cells. Pancreati...

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Detalles Bibliográficos
Autores principales: Chen, Suqin, Han, Junying, Liu, Yeqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559390/
https://www.ncbi.nlm.nih.gov/pubmed/26335571
http://dx.doi.org/10.1371/journal.pone.0137583