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Genotoxic, Cytotoxic, Antigenotoxic, and Anticytotoxic Effects of Sulfonamide Chalcone Using the Ames Test and the Mouse Bone Marrow Micronucleus Test

Chalcones present several biological activities and sulfonamide chalcone derivatives have shown important biological applications, including antitumor activity. In this study, genotoxic, cytotoxic, antigenotoxic, and anticytotoxic activities of the sulfonamide chalcone N-{4-[3-(4-nitrophenyl)prop-2-...

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Detalles Bibliográficos
Autores principales: Silva, Carolina Ribeiro e, Borges, Flávio Fernandes Veloso, Bernardes, Aline, Perez, Caridad Noda, Silva, Daniela de Melo e, Chen-Chen, Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559391/
https://www.ncbi.nlm.nih.gov/pubmed/26335560
http://dx.doi.org/10.1371/journal.pone.0137063