Regulation of hedgehog Ligand Expression by the N-End Rule Ubiquitin-Protein Ligase Hyperplastic Discs and the Drosophila GSK3β Homologue, Shaggy

Hedgehog (Hh) morphogen signalling plays an essential role in tissue development and homeostasis. While much is known about the Hh signal transduction pathway, far less is known about the molecules that regulate the expression of the hedgehog (hh) ligand itself. Here we reveal that Shaggy (Sgg), the...

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Detalles Bibliográficos
Autores principales: Moncrieff, Sophie, Moncan, Matthieu, Scialpi, Flavia, Ditzel, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559392/
https://www.ncbi.nlm.nih.gov/pubmed/26334301
http://dx.doi.org/10.1371/journal.pone.0136760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559392/
https://www.ncbi.nlm.nih.gov/pubmed/26334301
http://dx.doi.org/10.1371/journal.pone.0136760

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