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Meta-Analysis of Large-Scale Toxicogenomic Data Finds Neuronal Regeneration Related Protein and Cathepsin D to Be Novel Biomarkers of Drug-Induced Toxicity

Undesirable toxicity is one of the main reasons for withdrawing drugs from the market or eliminating them as candidates in clinical trials. Although numerous studies have attempted to identify biomarkers capable of predicting pharmacotoxicity, few have attempted to discover robust biomarkers that ar...

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Detalles Bibliográficos
Autores principales: Kim, Hyosil, Kim, Ju-Hwa, Kim, So Youn, Jo, Deokyeon, Park, Ho Jun, Kim, Jihyun, Jung, Sungwon, Kim, Hyun Seok, Lee, KiYoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559398/
https://www.ncbi.nlm.nih.gov/pubmed/26335687
http://dx.doi.org/10.1371/journal.pone.0136698