Intracellular Survival of Leishmania major Depends on Uptake and Degradation of Extracellular Matrix Glycosaminoglycans by Macrophages

Leishmania parasites replicate within the phagolysosome compartment of mammalian macrophages. Although Leishmania depend on sugars as a major carbon source during infections, the nutrient composition of the phagolysosome remains poorly described. To determine the origin of the sugar carbon source in...

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Detalles Bibliográficos
Autores principales: Naderer, Thomas, Heng, Joanne, Saunders, Eleanor C., Kloehn, Joachim, Rupasinghe, Thusitha W., Brown, Tracey J., McConville, Malcolm J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559419/
https://www.ncbi.nlm.nih.gov/pubmed/26334531
http://dx.doi.org/10.1371/journal.ppat.1005136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559419/
https://www.ncbi.nlm.nih.gov/pubmed/26334531
http://dx.doi.org/10.1371/journal.ppat.1005136

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