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MicroRNA-214 Promotes Apoptosis in Canine Hemangiosarcoma by Targeting the COP1-p53 Axis

MicroRNA-214 regulates both angiogenic function in endothelial cells and apoptosis in various cancers. However, the regulation and function of miR-214 is unclear in canine hemangiosarcoma, which is a spontaneous model of human angiosarcoma. The expression and functional roles of miR-214 in canine he...

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Detalles Bibliográficos
Autores principales: Heishima, Kazuki, Mori, Takashi, Sakai, Hiroki, Sugito, Nobuhiko, Murakami, Mami, Yamada, Nami, Akao, Yukihiro, Maruo, Kohji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559432/
https://www.ncbi.nlm.nih.gov/pubmed/26335793
http://dx.doi.org/10.1371/journal.pone.0137361