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Examination of the Effects of Heterogeneous Organization of RyR Clusters, Myofibrils and Mitochondria on Ca(2+) Release Patterns in Cardiomyocytes
Spatio-temporal dynamics of intracellular calcium, [Ca(2+)](i), regulate the contractile function of cardiac muscle cells. Measuring [Ca(2+)](i) flux is central to the study of mechanisms that underlie both normal cardiac function and calcium-dependent etiologies in heart disease. However, current i...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559435/ https://www.ncbi.nlm.nih.gov/pubmed/26335304 http://dx.doi.org/10.1371/journal.pcbi.1004417 |