A Gβ protein and the TupA Co-Regulator Bind to Protein Kinase A Tpk2 to Act as Antagonistic Molecular Switches of Fungal Morphological Changes

The human pathogenic fungus Paracoccidioides brasiliensis (Pb) undergoes a morphological transition from a saprobic mycelium to pathogenic yeast that is controlled by the cAMP-signaling pathway. There is a change in the expression of the Gβ-protein PbGpb1, which interacts with adenylate cyclase, dur...

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Detalles Bibliográficos
Autores principales: Janganan, Thamarai K., Chen, Gongyou, Chen, Daliang, Menino, João F., Rodrigues, Fernando, Borges-Walmsley, Maria I., Walmsley, Adrian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559445/
https://www.ncbi.nlm.nih.gov/pubmed/26334875
http://dx.doi.org/10.1371/journal.pone.0136866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559445/
https://www.ncbi.nlm.nih.gov/pubmed/26334875
http://dx.doi.org/10.1371/journal.pone.0136866

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