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Coordination between Translation and Degradation Regulates Inducibility of mGluR-LTD

Dendritic protein homeostasis is crucial for most forms of long-term synaptic plasticity, and its dysregulation is linked to a wide range of brain disorders. Current models of metabotropic glutamate receptor mediated long-term depression (mGluR-LTD) suggest that rapid, local synthesis of key protein...

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Detalles Bibliográficos
Autores principales: Klein, Matthew E., Castillo, Pablo E., Jordan, Bryen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559485/
https://www.ncbi.nlm.nih.gov/pubmed/25753412
http://dx.doi.org/10.1016/j.celrep.2015.02.020